Research

Research is a significant part of our work. It puts us at the forefront of what we do and ensures that we are always up to date with the latest research and development.

Our Consultants, who have over 70 years of eye surgical experience between them, have all trained in Ireland with further subspecialised advanced training in the Mayo Clinic, USA, Toronto and Moorfields Eye Hospital London.

Professor Michael O’Keeffe and the team and the Mater Private Eye Laser Centre host an international refractive eye laser conference every 2 years in Dublin and this is attended by some of the leading eye surgeons from all over the world.

Having published 100’s of international peer reviewed papers and books on refractive surgery, our own consultants are also invited to speak all over the world, and have been awarded over 100 international and national prizes and awards in recognition of their cutting edge clinical research. Below is a sample of international peer reviewed research articles published by the doctors at the Eye Laser Centre:

Twelve-month follow-up of the Artiflex toric phakic intraocular lens.

Guerin MB, Treacy MP, O’Keeffe M.

Eur J Ophthalmol. 2014 Jan-Feb;24(1):10-3.

Incidence of dislocated and subluxed iris-fixated phakic intraocular lens and outcomes following re-enclavation.

Moran S, Kirwan C, O’Keefe M, Leccisotti A, Moore T.

Clin Experiment Ophthalmol. 2014 Mar 10.

Bevacizumab versus diode laser in stage 3 posterior retinopathy of prematurity.

Moran S, O’Keefe M, Hartnett C, Lanigan B, Murphy J, Donoghue V.

Acta Ophthalmol. 2014 Jan 16.

Corneal approach to hyperopic presbyopia treatment: six-month outcomes of a new multifocal excimer laser in situ keratomileusis procedure.

Ryan A, O’Keefe M.

J Cataract Refract Surg. 2013 Aug;39(8):1226-33.

Excimer laser photorefractive keratectomy for low to moderate myopia using a 5.0 mm treatment zone and no transitional zone: 16-year follow-up.

Guerin MB, Darcy F, O’Connor J, O’Keeffe M.

J Cataract Refract Surg. 2012 Jul;38(7):1246-50.

Safety, efficacy, and effect of foldable phakic iris-claw intraocular lenses on higher-order aberrations: Two-year follow-up.

Qasem Q, Dooley IJ, D’Arcy F, O’Keefe M.

J Cataract Refract Surg. 2012 Nov;38(11):2053-4.

Tear osmolarity in premature infants.

Ryan A, Lanigan B, O’Keefe M.

J Pediatr Ophthalmol Strabismus. 2012 Nov-Dec;49(6):348-52.

Comparison of dry-eye disease severity after laser in situ keratomileusis and laser-assisted subepithelial keratectomy.

Dooley I, D’Arcy F, O’Keefe M.

J Cataract Refract Surg. 2012 Jun;38(6):1058-64.

Foldable iris-fixated intraocular lens implantation in children.

Ryan A, Hartnett C, Lanigan B, O’Keefe M.

Acta Ophthalmol. 2012 Sep;90(6):e458-62.

Wavefront-guided and aspheric ablation for myopia — one-year results of the zyoptix personalized treatment advanced algorithm.

Ryan A, O’Keefe M

Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurity.

O’Keefe M.

Ir Med J. 2011 Jul-Aug;104(7):197.

Ten year follow up of laser in situ keratomileusis for all levels of myopia.

D’Arcy FM, Kirwan C, O’keefe M.

Acta Ophthalmol. 2012 Jun;90(4):e335-6.

Informed consent in refractive eye surgery: learning from patients and the courts.

Guerin M, O’Keeffe M.

Ir Med J. 2012 Sep;105(8):282-3

Vision-related quality of life assessment using the NEI-VFQ-25 in adolescents and young adults with a history of congenital cataract.

Kirwan C, Lanigan B, O’Keefe M.

J Pediatr Ophthalmol Strabismus. 2012 Jan-Feb;49(1):26-31.

Age-dependent rat retinal ganglion cell susceptibility to apoptotic stimuli: implications for glaucoma.

Guerin MB, Donovan M, McKernan DP, O’Brien CJ, Cotter TG.

Clin Experiment Ophthalmol. 2011 Apr;39(3):243-51.

Complications and visual prognosis in children with aniridia.

Lee H, Meyers K, Lanigan B, O’Keefe M.

J Pediatr Ophthalmol Strabismus. 2010 Jul-Aug;47(4):205-10;

Laser epithelial keratomileusis in 2010 – a review.

O’Keefe M, Kirwan C.

Clin Experiment Ophthalmol. 2010 Mar;38(2):183-91.

5-year prospective follow-up of Artisan phakic intraocular lenses for the correction of myopia, hyperopia and astigmatism.

Qasem Q, Kirwan C, O’Keefe M.

Ophthalmologica. 2010;224(5):283-90.

Diet and visually significant cataracts in galactosaemia: is regular follow up necessary?

Widger J, O’Toole J, Geoghegan O, O’Keefe M, Manning R.

J Inherit Metab Dis. 2010 Apr;33(2):129-32.

Choroidal melanoma in a 7-year-old child treated by trans-scleral local resection.

Russo A, Coupland SE, O’Keefe M, Damato BE.

Graefes Arch Clin Exp Ophthalmol. 2010 May;248(5):747-9.

Select item 20074288

Prospective contralateral eye study to compare conventional and wavefront-guided laser in situ keratomileusis.

D’Arcy F, Kirwan C, Qasem Q, O’Keefe M.

Acta Ophthalmol. 2012 Feb;90(1):76-80.

One year follow-up of contrast sensitivity following conventional laser in situ keratomileusis and laser epithelial keratomileusis.

Townley D, Kirwan C, O’Keefe M.

Acta Ophthalmol. 2012 Feb;90(1):81-5.

Surgical management of heavy eye phenomenon.

Siah WF, Guerin MB, Flitcroft I, Fulcher T.

Orbit. 2010 Oct;29(5):259-61.

Refractive surgery in patients with accommodative and non-accommodative strabismus: 1-year prospective follow-up.

Kirwan C, O’Keefe M, O’Mullane GM, Sheehan C.

Br J Ophthalmol. 2010 Jul;94(7):898-902.

Episcleritis following keratorefractive surgery.

D’Arcy F, Kirwan C, O’Keefe M.

Br J Ophthalmol. 2009 Nov;93(11):1554.

Cataract surgery and primary intraocular lens implantation in children < or = 2 years old in the UK and Ireland: finding of national surveys.

Solebo AL, Russell-Eggitt I, Nischal KK, Moore AT, Cumberland P, Rahi JS; British Isles Congenital Cataract Interest Group.

Br J Ophthalmol. 2009 Nov;93(11):1495-8.

Transient, complete loss of vision secondary to posterior diffusion of an ophthalmic viscosurgical device-lidocaine solution during complicated phacoemulsification.

Falzon K, Guerin MB, Fulcher T.

J Cataract Refract Surg. 2009 Aug;35(8):1472-3. doi: 10.1016/j.jcrs.2009.04.024.

A case of relapsing flitting bilateral idiopathic orbital inflammation.

Browne MA, O’Keefe M, Twomey E, Donoghue V, Ryan S.

Pediatr Radiol. 2009 Dec;39(12):1361-4.

Glaucoma in aphakic and pseudophakic eyes following surgery for congenital cataract in the first year of life.

Kirwan C, Lanigan B, O’Keefe M.

Acta Ophthalmol. 2010 Feb;88(1):53-9.

Prophylaxis of diffuse lamellar keratitis with intraoperative interface steroids in LASIK.

Ng EY, Thinagaran S, Kinsella F, O’Keefe M.

J Refract Surg. 2009 Mar;25(3):306-11

Prophylaxis of diffuse lamellar keratitis with intraoperative interface steroids in LASIK.

Ng EY, Thinagaran S, Kinsella F, O’Keefe M.

J Refract Surg. 2009 Mar;25(3):306-11

Aniridia: current pathology and management.

Lee H, Khan R, O’Keefe M.

Acta Ophthalmol. 2008 Nov;86(7):708-15.

Laser-assisted subepithelial keratectomy retreatment after laser in situ keratomileusis.

Saeed A, O’Doherty M, O’Doherty J, O’Keefe M.

J Cataract Refract Surg. 2008 Oct;34(10):1736-41.

Visual outcomes and graft survival following corneal transplants: the need for an Irish National Corneal Transplant Registry.

Guerin M, O’ Connell E, Walsh C, Fulcher T.

Ir J Med Sci. 2008 Jun;177(2):107-10.

Comparative study of higher-order aberrations after conventional laser in situ keratomileusis and laser epithelial keratomileusis for myopia using the technolas 217z laser platform.

Kirwan C, O’Keefe M.

Am J Ophthalmol. 2009 Jan;147(1):77-83.

Golf–recognising the risk of severe eye injury.

Townley D, Kirwan C, O’Keefe M.

Ir Med J. 2008 Jun;101(6):167-9.

Postcataract surgery outcome in a series of infants and children with Down syndrome.

Gardiner C, Lanigan B, O’Keefe M.

Br J Ophthalmol. 2008 Aug;92(8):1112-6.

Corneal hysteresis and corneal resistance factor in keratoectasia: findings using the Reichert ocular response analyzer.

Kirwan C, O’Malley D, O’Keefe M.

Ophthalmologica. 2008;222(5):334-7.

Measurement of intraocular pressure in LASIK and LASEK patients using the Reichert Ocular Response Analyzer and Goldmann applanation tonometry.

Kirwan C, O’Keefe M.

J Refract Surg. 2008 Apr;24(4):366-70.

A double-blind randomized control study to determine the effect of Visthesia viscoelastic substance on pain following LASEK.

Kirwan C, Mulqueen C, O’Keefe M.

Ophthalmologica. 2008;222(4):229-31. doi: 10.1159/000130071. Epub 2008 May

Central retinal artery occlusion due to paroxysmal atrial fibrillation: the importance of Holter monitoring.

Kirwan C, Sugrue D, O’Keefe M.

Ir J Med Sci. 2008 Sep;177(3):277-8.

Higher order aberrations in children with amblyopia.

Kirwan C, O’Keefe M.

J Pediatr Ophthalmol Strabismus. 2008 Mar-Apr;45(2):92-6.

Worldwide geographical distribution of ophthalmology publications.

Guerin MB, Flynn TH, Brady J, O’Brien CJ.

Int Ophthalmol. 2009 Dec;29(6):511-6.

Fundus fluorescein angiographic characterization of diffuse choroidal hemangiomas.

Horgan N, O’Keefe M, McLoone E, Lanigan B.

J Pediatr Ophthalmol Strabismus. 2008 Jan-Feb;45(1):26-30.

Screening for retinopathy of prematurity.

O’Keefe M, Kirwan C.

Early Hum Dev. 2008 Feb;84(2):89-94.

Association between amblyopia and HOAs.

Kirwan C, O’Keefe M.

J Cataract Refract Surg. 2007 Nov;33(11):1833; author reply 1833-5.

Intraocular lenses in children.

O’Keefe M.

Acta Ophthalmol Scand. 2007 Nov;85(7):696-7.

Corneal hysteresis using the Reichert ocular response analyser: findings pre- and post-LASIK and LASEK.

Kirwan C, O’Keefe M.

Acta Ophthalmol. 2008 Mar;86(2):215-8. Epub 2007 Sep 21.

Changing pattern of childhood blindness.

Khan RI, O’Keefe M, Kenny D, Nolan L.

Ir Med J. 2007 May;100(5):458-61.

Importance of fundoscopy in refractive surgery.

Brady J, O’Keefe M, Kilmartin D.

J Cataract Refract Surg. 2007 Sep;33(9):1602-

Long-term results of laser in situ keratomileusis for high myopia: risk for ectasia.

Condon PI, O’Keefe M, Binder PS.

J Cataract Refract Surg. 2007 Apr;33(4):583-90.

A key role for calpains in retinal ganglion cell death.

McKernan DP, Guerin MB, O’Brien CJ, Cotter TG.

Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5420-30.

Analysis of the visual and refractive outcome following laser in situ keratomileusis (LASIK) retreatment over a four-year follow-up period.

Saeed A, O’Doherty M, O’Doherty J, O’Keefe M.

Int Ophthalmol. 2007 Feb;27(1):23-9. Epub 2007 Mar 24

Pediatric refractive surgery.

O’Keefe M, Kirwan C.

J Pediatr Ophthalmol Strabismus. 2006 Nov-Dec;43(6):333-6. Review.

Management of capillary hemangiomas.

Gold R, O’Keefe M, Langer P.

J Pediatr Ophthalmol Strabismus. 2006 Nov-Dec;43(6):326-30. No abstract available.

Corneal hysteresis and intraocular pressure measurement in children using the reichert ocular response analyzer.

Kirwan C, O’Keefe M, Lanigan B.

Am J Ophthalmol. 2006 Dec;142(6):990-2. Epub 2006 Sep 1. Erratum in: Am J Ophthalmol. 2007 Oct;144(4):642.

Paediatric aphakic glaucoma.

Kirwan C, O’Keefe M.

Acta Ophthalmol Scand. 2006 Dec;84(6):734-9. Review.

Taxane-resistant lymphoepithelial-like carcinoma: excellent response to VIP chemotherapy.

Duffy AG, Wyse G, Horgan AM, O’Keefe M, O’Reilly S, Breathnach OS.

Ir J Med Sci. 2006 Jul-Sep;175(3):64-5.

Long-term refractive and biometric outcomes following diode laser therapy for retinopathy of prematurity.

McLoone EM, O’Keefe M, McLoone SF, Lanigan BM.

J AAPOS. 2006 Oct;10(5):454-9.

Stereopsis in refractive surgery.

Kirwan C, O’keefe M.

Am J Ophthalmol. 2006 Aug;142(2):218-22

Retinal ganglion cells: dying to survive.

Guerin MB, McKernan DP, O’Brien CJ, Cotter TG.

Int J Dev Biol. 2006;50(8):665-74. Review. No abstract available.